How Long Does Soma Stay In Your System

Soma is a drug used to inhibit the central nervous system so as to relax muscles. Soma contains a main active ingredient known as Carisoprodol, which was firstly synthesized in 1950 as an anti-septic. Soma is nowadays used to relieve pain, induce sedation, and muscles relaxation. Sedation is repeatedly reported as the commonest effect that makes Soma abused. Examples of drugs containing this same ingredient include: Vanadom, Carisol, Carisoma, Somadril and Aciprodol.

How does Soma work

The exact mechanism of action of Soma is not fully understood. Generally, in order to inhibit the central nervous system, Soma and its metabolites improve the activities of certain receptors in the brain known as gamma-aminobutyric-acid (GABAA), which in turn results in significant improvements in the effects of a substance known as GABA and its ability to bind to the previous receptors. In addition, Soma inhibits the communication between neurons. That’s how Soma is thought to decrease pain sensation, induce sedation, and relax muscles.

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How long does Soma stay in your system

Up to 12 hours post-administration, the main active ingredient of Soma (Carisoprodol) can stay in your system. The reason is that the half-life of Carisoprodol is around 2 hours, which means that within 2 hours post-administration, 50% of the administered dose of Carisoprodol will no longer be active in your system, and so on till your body gets rid of the whole dose.

More importantly, Carisoprodol is metabolized (transformed) in the system into another substance known as meprobamate, which is eliminated from the system within an average half-life of 10 hours. Therefore, up to more than 2.5 days post-transformation, meprobamate can stay in your system.

Other factors

In addition, there are other factors that can significantly affect how long Soma and its metabolite can stay in your system, including:

  • your age
  • your body mass
  • whether you’re a light or a heavy user of Soma
  • the administered dose. For example, if you administer an overdose, Soma and its metabolite will undoubtedly stay longer in your system.
  • your metabolic rate of drugs, which determines how quickly your system is able to get rid of Soma and its metabolite.

Will Soma show on a drug test?

Taking into consideration that Soma is a muscle relaxant, Soma is not supposed to show on common drug tests; unless it is specifically tested for. However, as recently Soma has been scheduled as a controlled substance in many states of the U.S., there is increasingly anecdotal evidence reporting that Soma showed up in the drug tests of some users. In addition, some claims that Soma sometimes test false positive for morphine and benzodiazepines.

Furthermore, the results of drug tests significantly depend on the factors shown below, which are able to result in showing negative results.

  1. the route of administration
  2. the type of the tests you are required to undergo
  3. the time the test is performed. Each test is only valid within a certain time frame, which means that what a certain test can detect at a certain moment; another test can’t at the same moment.
  4. individual factors that differ from a person to another, as shown above, such as the functioning ability of your system to eliminate Soma and its metabolite.

How long is Soma detectable


Starting from 1-4 hours, carisoprodol is likely detectable in blood; while meprobamate metabolite takes around 2.5 hours post-administration to show up. Up to 24 hours post-administration, both Soma and its metabolite are likely detectable in your blood.


Up to 3-5 days post-administration, meprobamate metabolite is likely detectable in your urine; while that duration is shorter, in case of carisoprodol, as it is eliminated more quickly than meprobamate.

Hair, saliva and fingernails

Up to 1 month post administration, Soma and its metabolites are likely detectable in your hair; while saliva, Soma and its metabolites can be detected within much shorter duration post-administration, which is even shorter than that of urine tests. On the other side, fingernails are rarely considered for soma testing.

What drug tests will show the presence of Soma in the system

  • Blood analysis
  • Urinalysis
  • Hair-based tests, including: Gas chromatography/mass spectrometry, ELISA (enzyme linked immunosorbent assays)
  • Saliva-based tests, such as high performance liquid chromatography (HPLC)

How is Soma stored in the body

After oral administration, Soma is readily absorbed from the gastrointestinal tract, rising in blood stream till it achieves a peak level in plasma. For example, if you administered a 350-mg dose, it may take carisoprodol around 2-4 hours to reach its peak plasma concentration, diffusing to the central nervous system where it works.

Then, carisoprodol is metabolized (transformed), forming 3 other substances, including meprobamate, hydroxycarisoprodol, and hydroxymeprobamate, which stay in the system for a while. Afterwards, within the previously-mentioned half-lives, carisoprodol and each metabolite is eliminated to outside the system through both urine and feces. While alittle amount of the metabolites is stored in hair; around 1% of the main ingredient remains unchanged in the system, and so is excreted in the urine.


How Long Does Soma Stay In Your System
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Daniel Miller
Daniel Miller

Hey there! I'm Daniel, a 35 years old Ph.D. in pharmacology and a member of THC Detox. My research into cannabis shows how cannabis affects health, including how cannabinoids can be used in the treatment of various diseases. I've got a long list of scientific and medical publications that show the positive effects of cannabis clearly.

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