How Long Does Valium Stay In System
Valium contains a main active ingredient known as diazepam, which belongs to a group of drugs known as benzodiazepines. Valium is mainly used to treat muscle spasms (convulsions), anxiety disorders, seizures and the symptoms resulting from alcohol withdrawal. Diazepam Intensol, Diastat, and Diastat Pediatric are examples of common brands containing the same ingredient of Valium.
- How does Valium work
- How long does Valium stay in your system
- Other factors
- Will Valium show on a drug test?
- How long is Valium detectable
- What drug tests will show the presence of Valium in the system
- How is Clonazepam stored in the body
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How does Valium work
Valium binds to certain receptors in the brain known as gamma aminobutyric acid (GABA), resulting in improving the activities of a main inhibitory substance known as GABA. That’s how Valium inhibits the activities of the central nervous system, resulting in decreasing anxiety, relieving convulsions and inducing a state of sedation. The sedative and hypnotic effects of Valium are likely to cause it to be amongst the commonly misused drugs.
How long does Valium stay in your system
How long Valium stays in your system is directly dependent on the half-life of diazepam, as well as another substance that results from diazepam metabolism (transformation) in the system, which is known as nordiazepam.
Up to 14 days post-administration, diazepam is likely to stay in your system. The reason is that the half-life of diazepam ranges from 30-56 hours, which means that within 30-56 hours post-administration, 50% of the administered dose of diazepam will no longer be active in your system, and so on till the full dose is eliminated.
Additionally, up to 25 days post-administration, nordiazepam can stay in your system, as it has a half-life ranging from 40-100 hours.
Importantly, there are other factors that can significantly affect the duration Valium stays in your system. Those factors differ from a person to another, including:
- your age
- your body mass
- the administered dose. Surely, the higher the dose you administer, the longer duration Valium can stay in your system.
- whether you’re a mild or a chronic user of Valium
- your metabolic rate of drugs. That determines how quickly your body is able to get rid of Valium.
Will Valium show on a drug test?
Yes, of course, Valium will show on a drug test, such as a standard 10-panel drug tests, and even a standard 7-panel drug urine test, as those tests screen for certain substances, including benzodiazepines.
Furthermore, there are factors that can significantly affect drug tests’ results, as follows:
- the type of the tests you are required to undergo
- the time the test is performed, as each test is only valid within a certain time frame. Therefore, what a certain test can show at a certain moment; another test can’t.
- individual factors that differ from a person to another, as shown above.
How long is Valium detectable
Urine and blood
Valium is more likely to show in blood samples taken from chronic users of Valium, compared to light users. On the side, urine samples offer a better medium to detect diazepam and its metabolites, especially oxazepam, within many days and even weeks post-administration, depending on individual variability between people.
Hair, saliva and fingernails
Up to 3 months post-administration, Valium is likely detectable in hair; while both saliva and fingernails are rarely considered for benzodiazepines testing. In order for detecting Valium in saliva, that requires chronically administering high doses of Valium, or using laboratory-based tests such as a combination of Gas Chromatography (GC) and Mass Spectrometry (MS).
What drug tests will show the presence of Valium in the system
- Blood analysis
- Hair-based tests, including: Gas chromatography/mass spectrometry, ELISA (enzyme linked immunosorbent assays)
- Saliva-based tests, such as High performance liquid chromatography (HPLC)
How is Clonazepam stored in the body
Within 1-2 hours post-administration, around 90% of the administered Valium (diazepam) is absorbed from the gastrointestinal tract, and rises in blood stream till it reaches its peak concentration in plasma.
With blood stream, diazepam diffuses through different body parts till it passes the blood brain barrier towards the brain. In addition, around 98% of diazepam binds to different plasma proteins in the body. That may account for the prolonged duration diazepam and its metabolites stay in the system.
Diazepam is then metabolized (transformed) into other substances, nordiazepam and oxazepam, for example. Within the previously-mentioned half-lives, diazepam and its metabolites are eliminated to outside the body; while some of diazepam metabolites are stored in hair.
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